ea0056gp108 | Diabetes Translational | ECE2018
Tarkun Ilhan
, Cakmak Yagmur
, Akyay Zeynep
, Selek Alev
, Canturk Zeynep
, Cetinarslan Berrin
Objective: Insulin insufficiency which is the result of deficiency of β-cells is the common feature for all types of diabetes. Therefore protection of functional β-cell mass is the keystone of diabetes treatment. Betatrophin, a newly determined hormone, has been identified as a potent stimulator that increases the production and expansion of β-cells in mice. However, very little is known about the physiological role of betatrophin in h...